The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 12, 2007

Filed:

Jun. 28, 2002
Applicants:

Merry R. Sherman, San Carlos, CA (US);

Alexa L. Martinez, San Jose, CA (US);

Shyam S. Bhaskaran, New York, NY (US);

L. David Williams, Fremont, CA (US);

Mark G. P. Saifer, San Carlos, CA (US);

John A. French, Santa Cruz, CA (US);

Inventors:

Merry R. Sherman, San Carlos, CA (US);

Alexa L. Martinez, San Jose, CA (US);

Shyam S. Bhaskaran, New York, NY (US);

L. David Williams, Fremont, CA (US);

Mark G. P. Saifer, San Carlos, CA (US);

John A. French, Santa Cruz, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/96 (2006.01); C12N 9/56 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods are provided for the stabilization of proteinases by the covalent attachment of or admixture with water-soluble polymers. The resultant stabilized proteinases have increased stability under the harsh conditions used in industrial genomics, which permits their use in the extraction and isolation of nucleic acids and the identification of disease-related prion proteins at elevated temperatures in solutions containing chaotropic agents, such as sodium dodecyl sulfate, urea or guanidinium salts, conferring advantages for robotic applications.


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