Company Filing History:
Years Active: 2006-2014
Title: The Innovative Contributions of Martin Friedlander
Introduction
Martin Friedlander, an accomplished inventor based in Del Mar, California, has made significant strides in the field of biomedical science, particularly in the treatment of retinal degenerative diseases. With a remarkable portfolio of 15 patents, Friedlander's inventions embody the intersection of innovation and medical advancement.
Latest Patents
One of Friedlander's groundbreaking patents relates to the treatment of cone cell degeneration using transfected lineage negative hematopoietic stem cells. This method involves isolating specific stem cell populations from the bone marrow of mammals suffering from retinal degenerative diseases. The process includes transfecting these cells with genes that encode an antiangiogenic fragment of human tryptophanyl tRNA synthetase (TrpRS) and injecting them into the eye to inhibit cone cell degeneration. Additionally, he has developed methods for enhancing treatment by stimulating activated astrocytes through laser technology.
Another notable patent addresses tryptophanyl-tRNA synthetase-derived polypeptides that regulate angiogenesis. This invention includes isolated nucleic acid encoding polypeptides capable of inhibiting angiogenesis or neovascularization, with specific sequences that ensure efficacy in therapeutic applications.
Career Highlights
Friedlander has held influential roles at prominent institutions such as The Scripps Research Institute and Merck Patent Gmbh. His extensive research and development efforts at these organizations have greatly contributed to advancements in pharmaceutical therapies and regenerative medicine.
Collaborations
Throughout his career, Martin Friedlander has collaborated with esteemed colleagues like Paul Schimmel and Keisuke Wakasugi. These partnerships have fostered an environment of creativity and innovation, further enhancing the impact of his inventions in the scientific community.
Conclusion
Martin Friedlander's contributions to science and medicine continue to resonate through his patented innovations. His work in preventing retinal cell degeneration and regulating angiogenesis not only showcases his inventiveness but also holds the potential to improve the quality of life for many individuals affected by debilitating diseases. As a pioneering inventor, Friedlander's legacy will undoubtedly inspire future generations in the realm of biomedical innovation.