The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 2006
Filed:
May. 30, 1997
Peter C. Brooks, West Harrison, NY (US);
David A. Cheresh, Encinitas, CA (US);
Martin Friedlander, Del Mar, CA (US);
Peter C. Brooks, West Harrison, NY (US);
David A. Cheresh, Encinitas, CA (US);
Martin Friedlander, Del Mar, CA (US);
The Scripps Research Institute, La Jolla, CA (US);
Abstract
The present invention describes methods for inhibiting angiogenesis in tissues using vitronectin αβantagonists. The αβ-mediated angiogenesis is correlated with exposure to cytokines including vascular endothelial growth factor, transforming growth factor-α and epidermal growth factor. Inhibition of αβ-mediated angiogenesis is particularly preferred in vascular endothelial ocular neovascular diseases, in tumor growth and in inflammatory conditions, using therapeutic compositions containing αβantagonists.