The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 23, 2010
Filed:
Apr. 28, 2004
Martin Friedlander, Del Mar, CA (US);
Atsushi Otani, Maebashi, JP;
Karen Da Silva, Irvine, CA (US);
Stacey (Hanekamp) Moreno, Spring Valley, CA (US);
Martin Friedlander, Del Mar, CA (US);
Atsushi Otani, Maebashi, JP;
Karen Da Silva, Irvine, CA (US);
Stacey (Hanekamp) Moreno, Spring Valley, CA (US);
The Scripps Research Institute, La Jolla, CA (US);
Abstract
Isolated, mammalian, adult bone marrow-derived, lineage negative hematopoietic stem cell populations (LinHSCs) contain endothelial progenitor cells (EPCs) capable of rescuing retinal blood vessels and neuronal networks in the eye. Preferably at least about 20% of the cells in the isolated LinHSCs express the cell surface antigen CD31 and not more than about 1 percent of the cells express Tie-2. The isolated LinHSC populations are useful for treatment of ocular vascular diseases.