Location History:
- Pittsburg, PA (US) (2013)
- Garrett Park, MD (US) (2015)
- Washington, DC (US) (2016 - 2017)
- Pittsburgh, PA (US) (2015 - 2024)
Company Filing History:
11 out of 1,869 
6 out of 3,540 
6 out of 507 
Years Active: 2013-2025
Title: An Insight into Mark Thomas Gladwin: Innovating Solutions for Carbon Monoxide Poisoning
Introduction
Mark Thomas Gladwin is an influential inventor based in Pittsburgh, PA. With a profound commitment to advancing medical treatments, he holds a remarkable portfolio of 17 patents. His innovative contributions primarily focus on addressing the critical issue of carboxyhemoglobinemia, a condition stemming from carbon monoxide poisoning.
Latest Patents
One of Gladwin's latest patents presents compositions and methods for the rapid elimination of carbon monoxide from hemoglobin. This ingenious antidote utilizes modified human globins, specifically neuroglobins and cytoglobins, which possess high affinity for carbon monoxide. By infusing these modified globins into the blood, they effectively sequester carbon monoxide, thereby mitigating its toxic effects on cellular respiration and oxygen transport.
Another significant patent details the methods of removing carbon monoxide from hemoglobin in both in vitro and in vivo settings. These methods are essential for treating carboxyhemoglobinemia and include administering reduced natural or artificial oxygen carriers. Additionally, this patent also outlines techniques for combatting cyanide and hydrogen sulfide poisoning using oxygen carriers.
Career Highlights
Throughout his career, Mark Thomas Gladwin has made substantial contributions while working at esteemed institutions. Notably, he has been associated with the University of Pittsburgh and The United States of America, as represented by the Secretary of the Department of Health and Human Services. His dedication to advancing medical science is unmatched, and his patents are a testament to his expertise and innovation.
Collaborations
Gladwin has collaborated with notable colleagues such as Daniel B. Kim-Shapiro and Jesus Tejero Bravo. Together, they have worked on groundbreaking research that aims to revolutionize the treatment of carbon monoxide poisoning and related conditions.
Conclusion
Mark Thomas Gladwin stands out as a visionary inventor whose work is transforming the medical landscape. His patents not only provide innovative solutions to crucial health issues but also demonstrate the impact of dedicated research and collaboration in the field of medical science. Through his contributions, countless lives can be saved, highlighting the importance of innovation in healthcare.