The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 13, 2021

Filed:

May. 19, 2017
Applicant:

University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);

Inventors:

Jason Joseph Rose, Pittsburgh, PA (US);

Qinzi Xu, Wexford, PA (US);

Mark T. Gladwin, Pittsburgh, PA (US);

Jesus Tejero Bravo, Pittsburgh, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/42 (2006.01); A61K 9/127 (2006.01); A61K 35/14 (2015.01); C01C 3/08 (2006.01); C07K 14/795 (2006.01); A61K 31/409 (2006.01); A61K 33/00 (2006.01); A61K 38/06 (2006.01);
U.S. Cl.
CPC ...
A61K 38/42 (2013.01); A61K 9/127 (2013.01); A61K 35/14 (2013.01); C01C 3/08 (2013.01); C07K 14/795 (2013.01); A61K 31/409 (2013.01); A61K 33/00 (2013.01); A61K 38/063 (2013.01);
Abstract

In vitro and in vivo methods of removing carbon monoxide from hemoglobin in blood or animal tissue are described. Methods of treating carboxyhemoglobinemia (carbon monoxide poisoning) in a subject are also described. The methods include administering natural or artificial oxygen carriers that are in their reduced form. Methods of producing a reduced oxygen carrier are further described. Methods of treating cyanide poisoning or hydrogen sulfide poisoning with oxygen carriers are also described.


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