The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 17, 2020

Filed:

Nov. 28, 2018
Applicant:

University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);

Inventors:

Mark Gladwin, Pittsburgh, PA (US);

Courtney E. Sparacino-Watkins, Pittsburgh, PA (US);

Michael Jurczak, Pittsburgh, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 3/10 (2006.01); A61K 31/7105 (2006.01); A61K 31/713 (2006.01); A61K 48/00 (2006.01); A61K 38/28 (2006.01);
U.S. Cl.
CPC ...
A61K 38/28 (2013.01); A61K 31/7105 (2013.01); A61K 48/0016 (2013.01); A61K 48/0066 (2013.01); A61P 3/10 (2018.01);
Abstract

A method of treating hyperglycemia, diabetes, metabolic syndrome, insulin resistance (insulin insensitivity), impaired glucose tolerance, high glucose levels, pulmonary hypertension, and/or a condition arising from any of the foregoing in a patient is provided. The method comprises knocking down mARC2 or mARC1 expression in the patient, or otherwise decreasing mARC2 and mARC1 activity in the patient.


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