The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 11, 2022

Filed:

Apr. 16, 2018
Applicant:

University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);

Inventors:

Mark Thomas Gladwin, Pittsburgh, PA (US);

Hunter Clay Champion, Pittsburgh, PA (US);

Edwin Parsley, Houston, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 59/00 (2006.01); A61K 33/00 (2006.01); A61K 31/04 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 33/00 (2013.01); A61K 9/007 (2013.01); A61K 9/0073 (2013.01); A61K 31/04 (2013.01);
Abstract

Disclosed herein are methods for treating acute or chronic heart failure using inorganic nitrite, such as sodium nitrite. The method includes administering to a subject in need of treatment a therapeutically effective amount of inorganic nitrite. The nitrite may be administered by inhalation and may be nebulized. The nitrite may be administered at an emitted dose or in an escalated titrated dose. The nitrite may be a liquid formulation or a dry powder formulation.


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