Location History:
- Kanagawa, JP (1994 - 2011)
- Tokyo, JP (1991 - 2015)
Company Filing History:
23 out of 58,130 
1 out of 30,040 
1 out of 11,665 Years Active: 1991-2015
Title: Innovations and Contributions of Makoto Hashimoto in Neurodegenerative Disease Treatment
Introduction
Makoto Hashimoto, located in Kanagawa, Japan, is a prolific inventor with a remarkable portfolio of 27 patents. His innovative work primarily focuses on neurodegenerative diseases, where he utilizes his expertise to develop novel treatment methodologies.
Latest Patents
Among Hashimoto's latest patents is a method for treating and/or preventing neurodegenerative diseases using an adiponectin receptor agonist. This invention aims to counteract synucleinopathies by targeting the suppression of α-synuclein aggregation and tau phosphorylation, alongside enhancing proteasomal activity. The patented method administers an effective dose of elements such as adiponectin and various compounds inducing its expression, providing a promising solution for battling these debilitating diseases. Additionally, he has devised a technology for detecting abnormalities in a processing apparatus, which adjusts the detection frequency based on the occurrence of signs indicating failure. This dual approach not only enhances treatment applications but also improves system reliability.
Career Highlights
Hashimoto's professional journey includes significant contributions through his engagements with major companies like Sony Corporation and Siemens Aktiengesellschaft. His work at these esteemed organizations has allowed him to hone his skills in research and development, resulting in impactful innovations.
Collaborations
Throughout his career, Hashimoto has collaborated with notable individuals such as Takeshi Matsushita and Takusei Sato. These partnerships have facilitated a rich exchange of ideas, ultimately contributing to the advancement of his research and the resultant patents.
Conclusion
Makoto Hashimoto's inventions illustrate the critical intersection of technology and healthcare, particularly in the realm of neurodegenerative disease treatment. His extensive patent portfolio reflects not only his innovative spirit but also his commitment to making significant strides in medical science. The advancements nurtured through his work continue to hold promise for improving the quality of life for individuals affected by these challenging conditions.