Madison, WI, United States of America

Lloyd M Smith

USPTO Granted Patents = 51 


Average Co-Inventor Count = 3.1

ph-index = 21

Forward Citations = 2,548(Granted Patents)

Forward Citations (Not Self Cited) = 2,499(Oct 12, 2025)


Inventors with similar research interests:


Location History:

  • Atlanta, GA (US) (1976 - 1977)
  • South Pasadena, CA (US) (1988 - 1993)
  • Columbia, LA (US) (1997)
  • Madison, WI (US) (1992 - 2023)

Company Filing History:


Years Active: 1976-2023

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51 patents (USPTO):Explore Patents

Title: Lloyd M. Smith: Innovator in RNA Technologies

Introduction: Lloyd M. Smith, based in Madison, WI, is a distinguished inventor renowned for his significant contributions to the field of molecular biology. With an impressive portfolio of 51 patents, he has made remarkable strides in developing innovative techniques that enhance genomic research and therapeutic applications.

Latest Patents: Among his latest patented inventions are groundbreaking methods for RNA-mediated gene assembly from DNA oligonucleotides. This invention focuses on utilizing RNA polymerase to generate RNA copies from surface-bound oligonucleotides, which then self-assemble into full-length RNA transcripts. These transcripts are pivotal for various applications, including protein expression. Another patent involves RNA array compositions and methods, particularly high-density RNA arrays. This innovation employs template DNA arrays to create modified RNA arrays, resulting in superior nuclease resistance and enhanced binding affinity RNA aptamer arrays. These advancements showcase Smith's dedication to pioneering techniques that propel genetic research forward.

Career Highlights: Lloyd M. Smith has had a notable career that includes pivotal roles at the Wisconsin Alumni Research Foundation and the California Institute of Technology. His work in these institutions has significantly influenced the landscape of molecular biology and biotechnology, emphasizing the continual advancement of RNA technologies.

Collaborations: Throughout his career, Smith has collaborated with notable peers, including Michael S. Westphall and Steven Fung. These collaborations have fostered a fruitful environment for innovation, leading to the development of transformative techniques in RNA research.

Conclusion: With a robust array of patents and substantial contributions to the scientific community, Lloyd M. Smith exemplifies the spirit of innovation in the modern landscape of biotechnology. His journey remains a testament to the impact of dedicated research and the ongoing pursuit of knowledge in the realm of RNA technologies.

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