The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 09, 2012
Filed:
Mar. 12, 2003
Lloyd M. Smith, Madison, WI (US);
Leroy E. Hood, Seattle, WA (US);
Michael W. Hunkapiller, San Carlos, CA (US);
Timothy Hunkapiller, Mercer Island, WA (US);
Charles R. Connell, Redwood City, CA (US);
Lloyd M. Smith, Madison, WI (US);
Leroy E. Hood, Seattle, WA (US);
Michael W. Hunkapiller, San Carlos, CA (US);
Timothy Hunkapiller, Mercer Island, WA (US);
Charles R. Connell, Redwood City, CA (US);
California Institute of Technology, Pasadena, CA (US);
Abstract
This invention provides a duplex comprising an oligonucleotide primer and a template, wherein the primer is coupled chemically to a chromophore or fluorophore so as to allow chain extension by a polymerase. In one embodiment, the primer is extended by a polymerase to generate the complement of the template. In a further embodiment, the extended primer is separated from the template for use in a number of methods, including sequencing reactions. Methods of generating these compositions of matter are further provided.