Company Filing History:
Years Active: 2005-2014
Title: Lesley B Pickford: Innovator in Therapeutic Solutions
Introduction
Lesley B Pickford is a prominent inventor based in Menlo Park, CA, known for her significant contributions to the field of therapeutic solutions. With a total of 12 patents to her name, she has made remarkable strides in addressing complex medical conditions.
Latest Patents
Among her latest patents, Lesley has developed methods for the therapy of inflammatory bowel disease using a type-1 interferon antagonist. This includes compositions and methods for treating conditions such as Celiac Disease, Crohn's Disease, and Ulcerative Colitis. The illustrative compositions comprise one or more anti-type 1 interferon antagonists, including anti-type 1 interferon receptor antibody antagonists and fragments, as well as polypeptides and small molecules that inhibit the interaction of type 1 interferon with its receptor (IFNAR). Additionally, she has created enzyme-cleavable prodrug compounds, which are modified forms of therapeutic agents that include a therapeutic agent, an oligopeptide, a stabilizing group, and, optionally, a linker group. These prodrugs are designed to be cleavable by the enzyme Thimet oligopeptidase (TOP), and methods for designing prodrugs utilizing TOP-cleavable sequences are also disclosed.
Career Highlights
Lesley has worked with notable companies such as Medarex Inc. and Medarex, LLC, where she has contributed her expertise in therapeutic innovations. Her work has been instrumental in advancing the understanding and treatment of various medical conditions.
Collaborations
Lesley has collaborated with esteemed colleagues, including Sanjeev Gangwar and Matthew H Nieder, further enhancing her research and development efforts.
Conclusion
Lesley B Pickford's innovative work in therapeutic solutions has made a significant impact in the medical field. Her patents reflect her dedication to improving patient care and advancing medical science.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.