The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 09, 2014

Filed:

Mar. 17, 2011
Applicants:

Lesley B. Pickford, Menlo Park, CA (US);

Christopher R. Bebbington, San Mateo, CA (US);

Geoffrey T. Yarranton, Burlingame, CA (US);

David King, Belmont, CA (US);

Inventors:

Lesley B. Pickford, Menlo Park, CA (US);

Christopher R. Bebbington, San Mateo, CA (US);

Geoffrey T. Yarranton, Burlingame, CA (US);

David King, Belmont, CA (US);

Assignee:

Medarex, L.L.C., Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2866 (2013.01); C07K 2317/24 (2013.01); C07K 2319/30 (2013.01); C07K 2316/96 (2013.01); A61K 2039/505 (2013.01);
Abstract

Compositions and methods for the therapy of Inflammatory Bowel Disease (IBD), including Celiac Disease, Crohn's Disease, and Ulcerative Colitis, are disclosed. Illustrative compositions comprise one or more anti-type 1 interferon antagonists, such as anti-type 1 interferon receptor antibody antagonists and fragments thereof, as well as polypeptides and small molecules that inhibit the interaction of type 1 interferon with its receptor (IFNAR).


Find Patent Forward Citations

Loading…