The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 04, 2007
Filed:
Dec. 22, 2004
Christopher R. Bebbington, San Mateo, CA (US);
Matthew H. Nieder, Seattle, WA (US);
Pina M. Cardarelli, San Carlos, CA (US);
Sanjeev Gangwar, San Mateo, CA (US);
Lesley B. Pickford, Menlo Park, CA (US);
Chin Pan, Los Altos, CA (US);
Christopher R. Bebbington, San Mateo, CA (US);
Matthew H. Nieder, Seattle, WA (US);
Pina M. Cardarelli, San Carlos, CA (US);
Sanjeev Gangwar, San Mateo, CA (US);
Lesley B. Pickford, Menlo Park, CA (US);
Chin Pan, Los Altos, CA (US);
Medarex, Inc., Princeton, NJ (US);
Abstract
The compounds of the invention are modified forms of therapeutic agents. A typical prodrug compound of the invention comprises a therapeutic agent, an oligopeptide, a stabilizing group and, optionally, a linker group. The prodrug is cleavable by the CD10 enzyme. Methods of treatment using the prodrug and methods of designing a prodrug are also disclosed.