Shanghai, China

Lei Fang

USPTO Granted Patents = 38 

 

 

Average Co-Inventor Count = 2.6

ph-index = 3

Forward Citations = 44(Granted Patents)


Company Filing History:


Years Active: 2016-2025

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38 patents (USPTO):

Title: Innovations of Lei Fang in the Field of Bispecific Antibodies

Introduction

Lei Fang is a prominent inventor based in Shanghai, China, known for his significant contributions to the field of biopharmaceutical innovations. With a remarkable portfolio consisting of 35 patents, he has made strides in the development of bispecific antibodies, a promising area in therapeutic applications targeted at cancer and other diseases.

Latest Patents

Two of Lei Fang's latest patents demonstrate his expertise in the creation of bispecific antibodies. The first patent, titled "Anti-PD-L1/anti-4-1BB bispecific antibodies and uses thereof," introduces an innovative antibody capable of effectively blocking the interactions between PD-L1 and its receptor PD-1, as well as between 4-1BB and its ligand. This bispecific antibody showcases high binding affinity to both PD-L1 and 4-1BB proteins, making it a potential groundbreaking therapeutic option.

The second patent, "Anti-PD-L1/anti-LAG3 bispecific antibodies and uses thereof," reveals another advanced bispecific antibody which can block interactions between PD-L1 and PD-1, as well as LAG3 and its ligand, such as MHC class II molecules and FGL1. This invention also emphasizes its high binding affinity to both the PD-L1 protein and the LAG3 protein, offering significant therapeutic possibilities. Additionally, it includes antibodies and fragments that have specificity to PD-L1 or LAG3 proteins alone and those that may target other antigens.

Career Highlights

Throughout his career, Lei Fang has been instrumental in advancing biopharmaceutical research and development. He has worked with esteemed organizations, including Semiconductor Manufacturing International Corporation in Shanghai and I-mab Biopharma in the United States. His role in these companies has contributed to the advancement of innovative therapeutic solutions, highlighting his impact on the industry.

Collaborations

Lei Fang has collaborated with notable individuals in the field, including Zhengyi Wang and Bingshi Guo. These partnerships reflect his commitment to fostering innovation and driving progress in the biopharmaceutical landscape.

Conclusion

In summary, Lei Fang’s contributions to the realm of bispecific antibodies mark him as a significant inventor in the field. With his latest patents showcasing advancements in immunotherapeutic options, he continues to play a crucial role in the development of innovative treatments that may lead to improved patient outcomes. His career demonstrates a dedication to research and collaboration, shaping the future of medical science.

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