The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2022
Filed:
Jan. 25, 2019
Applicant:
I-mab Biopharma Us Limited, Gaithersburg, MD (US);
Inventors:
Lei Fang, Shanghai, CN;
Feifei Cui, Shanghai, CN;
Haijuan Gu, Shanghai, CN;
Zhengyi Wang, Shanghai, CN;
Bingshi Guo, Shanghai, CN;
Jingwu Zang, Shanghai, CN;
Assignee:
I-Mab Biopharma US Limited, Gaithersburg, MD (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/46 (2006.01); C07K 16/28 (2006.01); C07K 14/54 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2827 (2013.01); A61P 35/00 (2018.01); C07K 14/5418 (2013.01); C07K 16/2818 (2013.01); C07K 2317/31 (2013.01); C07K 2317/55 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2319/32 (2013.01);
Abstract
Provided are fusion molecule having a PD-L1 inhibitor fused to a human IL-7 protein or fragment thereof through a peptide linker. The disclosed fusion molecules exhibited synergistic anti-tumor effects.