The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 24, 2024
Filed:
Aug. 21, 2019
Abl Bio Inc., Seongnam-Si, KR;
Eunyoung Park, Seongnam-Si, KR;
Yangsoon Lee, Seongnam-Si, KR;
Uijung Jung, Seongnam-Si, KR;
YoungKwang Kim, Seongnam-Si, KR;
Yeun Ju Kim, Seongnam-Si, KR;
Youngdon Pak, Seongnam-Si, KR;
Sang Hoon Lee, Seongnam-Si, KR;
Weon-Kyoo You, Seongnam-Si, KR;
Jaeho Jung, Seongnam-Si, KR;
Lei Fang, Shanghai, CN;
Wenqing Jiang, Shanghai, CN;
ABL BIO INC., Seongnam-Si, KR;
Abstract
The present disclosure provides an anti-PD-L1/anti-LAG3 bispecific antibody capable to effectively block the interactions between PD-L1 and its receptor PD-1 and between LAG3 and its ligand (e.g., a MHC class II molecule and FGL1). The bispecific antibody may have high binding affinity to both of a PD-L1 protein (e.g., a human PD-L1 protein) and a LAG3 protein (e.g., a human LAG3 protein). Also provided are antibodies and fragments that have specificity to the PD-L1 or LAG3 protein alone, or antibodies and fragments having additional specificity to one or more other antigens.