Ipswich, MA, United States of America

Laurence Ettwiller

USPTO Granted Patents = 11 

 

Average Co-Inventor Count = 5.0

ph-index = 3

Forward Citations = 21(Granted Patents)


Location History:

  • Ipswich, MA (US) (2019 - 2022)
  • Beverly, MA (US) (1999 - 2024)

Company Filing History:


Years Active: 1999-2024

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11 patents (USPTO):Explore Patents

Title: Laurence Ettwiller: Innovator in Nucleotide Analysis

Introduction

Laurence Ettwiller is a prominent inventor based in Ipswich, MA (US). He has made significant contributions to the field of molecular biology, particularly in the analysis of modified nucleotides. With a total of 11 patents to his name, Ettwiller's work has advanced our understanding of nucleic acids and their modifications.

Latest Patents

Ettwiller's latest patents include innovative methods and compositions for analyzing modified nucleotides. One notable patent focuses on identifying the presence, location, and phasing of methylated and/or hydroxymethylated cytosines in nucleic acids. This method involves reacting a portion of a nucleic acid sample with a dioxygenase and a glucosyltransferase, followed by a reaction with a cytidine deaminase to detect and map cytosines in DNA. Another significant patent provides a method for mapping the location, type, and strand of damaged and/or mismatched nucleotides in double-stranded DNA. This method utilizes a combination of nick translating activity, ligase, and a nucleotide mix to generate a product that contains modified nucleoside monophosphates at the site of the nick.

Career Highlights

Throughout his career, Laurence Ettwiller has worked with notable organizations, including New England Biolabs, Inc. His expertise in molecular biology and nucleotide analysis has positioned him as a leader in his field.

Collaborations

Ettwiller has collaborated with esteemed colleagues such as Romualdas Vaisvila and Theodore B Davis. Their combined efforts have contributed to the advancement of research in nucleotide analysis.

Conclusion

Laurence Ettwiller's innovative work in the field of nucleotide analysis has led to significant advancements in molecular biology. His contributions continue to influence research and applications in the study of nucleic acids.

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