Location History:
- Boston, MA (US) (2022)
- Arlington, MA (US) (2012 - 2024)
Company Filing History:
14 out of 1,210 
2 out of 1,274 
2 out of 1,696 
Years Active: 2012-2025
Title: The Innovative Contributions of Inventor Kwok-kin Wong
Introduction
Kwok-kin Wong, based in Arlington, MA, is a distinguished inventor with an impressive portfolio of 17 patents. His work primarily focuses on therapeutic approaches to combat cancer, specifically targeting crucial pathways involved in tumor growth and survival.
Latest Patents
Among his notable contributions, Wong has developed several groundbreaking patents. One of his latest patents is titled "Therapeutic targeting of mutant lung squamous cell carcinoma through RTK-RAS signaling inhibition." This patent outlines a method for treating lung squamous cell carcinoma (LUSC) by administering inhibitors of the RTK-Ras signaling pathway to individuals in need. Notably, the LUSC cells may carry mutations in the KMT2D gene. The patent emphasizes the use of SHP2 inhibitors and epidermal growth factor receptor (EGFR) inhibitors, with the potential for combination therapies to enhance treatment efficacy.
Another significant patent from Wong is "Combination therapy for treatment of LKB1 deficient cancers." This work provides methods to sensitize LKB1/STK11 deficient cancers to immune therapy. It includes a treatment method involving the administration of inhibitors targeting NAMPT, CD38, SHP2, CXCR1/2, HDAC4, and PARP in combination with immunotherapy to improve patient outcomes.
Career Highlights
Throughout his career, Kwok-kin Wong has been affiliated with prestigious institutions, including Dana-Farber Cancer Institute and the University of North Carolina at Chapel Hill. His dedication to cancer research and innovative approaches has significantly contributed to the understanding and treatment of various cancers.
Collaborations
Wong’s work has been enhanced through collaborations with esteemed colleagues such as Nathanael Schiander Gray and Pasi Antero Janne. These partnerships have allowed for the exchange of ideas and expertise, fostering advancements in cancer therapies.
Conclusion
Kwok-kin Wong stands out in the realm of innovation and invention, particularly in the field of cancer treatment. With a robust portfolio of patents, including significant advancements targeting lung squamous cell carcinoma and LKB1 deficient cancers, he continues to impact the medical community positively. His collaborative spirit and commitment to research are invaluable assets in the ongoing battle against cancer.