The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 02, 2024
Filed:
Sep. 03, 2021
Applicant:
New York University, New York, NY (US);
Inventors:
David Peng, Mohegan Lake, NY (US);
Kwok-Kin Wong, Arlington, MA (US);
Jiehui Deng, Port Washington, NY (US);
Assignee:
New York University, New York, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4545 (2006.01); A61K 31/497 (2006.01); A61K 31/505 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4545 (2013.01); A61K 31/497 (2013.01); A61K 31/505 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01);
Abstract
Provided are methods of sensitizing LKB1/STK11 deficient cancers to immune therapy. A method for treatment for LKB1/STK11 deficient cancers is provided comprising administration of inhibitor or inhibitors of one or more of NAMPT, CD38, SHP2, CXCR1/2, HDAC4 and PARP in combination with immunotherapy.