The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 07, 2017
Filed:
Nov. 17, 2011
Derek P. Dirocco, Brookline, MA (US);
Norman E. Sharpless, Chapel Hill, NC (US);
Jay C. Strum, Hillsborough, NC (US);
John E. Bisi, Apex, NC (US);
Patrick J. Roberts, Durham, NC (US);
Benjamin D. Humphreys, Brookline, MA (US);
Kwok-kin Wong, Arlington, MA (US);
Derek P. DiRocco, Brookline, MA (US);
Norman E. Sharpless, Chapel Hill, NC (US);
Jay C. Strum, Hillsborough, NC (US);
John E. Bisi, Apex, NC (US);
Patrick J. Roberts, Durham, NC (US);
Benjamin D. Humphreys, Brookline, MA (US);
Kwok-Kin Wong, Arlington, MA (US);
The University of North Carolina at Chapel Hill, Chapel Hill, NC (US);
G1 Therapeutics, Chapel Hill, NC (US);
Brigham and Women's Hospital, Boston, MA (US);
Abstract
The presently disclosed subject matter relates to methods and compositions for protecting cells and or tissues from damage due to ischemia. In particular, the presently disclosed subject matter relates to the protective action of cyclin dependent kinase 4/6 (CDK4/6) inhibitors administered to subjects that have been exposed to, or that are at risk of, ischemia.