Location History:
- Apex, NC (US) (2016 - 2022)
- Chapel Hill, NC (US) (2018 - 2023)
Company Filing History:
18 out of 48 
3 out of 8 
1 out of 2,961 
Years Active: 2016-2023
Title: The Innovative Contributions of John Emerson Bisi
Introduction: John Emerson Bisi, based in Apex, North Carolina, is a distinguished inventor with a remarkable portfolio of 22 patents. His work primarily focuses on developing improved compounds and methods aimed at protecting healthy cells during chemotherapy, ultimately revolutionizing cancer treatment.
Latest Patents: Bisi's recent inventions include groundbreaking advancements in the field of cancer treatment. One notable patent is for the "Transient protection of normal cells during chemotherapy." This invention addresses the need for protecting healthy cells, particularly hematopoietic stem and progenitor cells (HSPCs) and renal cells, from the damaging effects of DNA-damaging chemotherapeutic agents. The improved compounds developed act as selective and short, transiently-acting inhibitors of cyclin-dependent kinase 4/6 (CDK 4/6), providing a strategic safeguard for patients undergoing cancer therapies.
Another significant patent by Bisi is focused on "HSPC-sparing treatments for RB-positive abnormal cellular proliferation." This innovation proposes improved compounds and methods for treating RB-positive cancers while reducing the harmful impacts on healthy HSPCs. The compounds designed in this patent are highly selective, further enhancing treatment efficacy while preserving healthy cell integrity.
Career Highlights: Bisi has made substantial contributions to the field through his tenure at notable companies like G1 Therapeutics, Inc. and Gi Therapeutics, Inc. His expertise has helped shape innovative strategies that advance cancer treatment options, making a significant impact on patient care.
Collaborations: Throughout his career, John Emerson Bisi has collaborated with esteemed professionals, including Jay Copeland Strum and Patrick Joseph Roberts. These partnerships have facilitated the exchange of ideas and expertise, further enhancing the innovative landscape in which Bisi operates.
Conclusion: With an impressive array of patents and a commitment to advancing medical treatment, John Emerson Bisi stands out as a vital contributor to the field of oncology research. His innovations not only protect healthy cells during chemotherapy but also pave the way for more effective and safer cancer therapies in the future.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.