The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 19, 2019
Filed:
Mar. 13, 2017
G1 Therapeutics, Inc., Research Triangle Park, NC (US);
Jay Copeland Strum, Hillsborough, NC (US);
John E. Bisi, Apex, NC (US);
Patrick Joseph Roberts, Durham, NC (US);
Jessica A. Sorrentino, Durham, NC (US);
Hannah S. White, Chapel Hill, NC (US);
GI Therapeutics, Inc., Research Triangle Park, NC (US);
Abstract
This invention directed to methods for treating select RB-positive cancers and other Rb-positive abnormal cellular proliferative disorders using CDK4/6 inhibitors in specific dosing and combination or alternation regimes. In one aspect, treatments of select RB-positive cancers are disclosed using specific CDK4/6 inhibitors in combination or alternation with another chemotherapeutic, for example, an additional kinase inhibitor, PD-1 inhibitor, or BCL-2 inhibitor, or combination thereof.