The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 11, 2023

Filed:

Apr. 24, 2015
Applicants:

Dana-farber Cancer Institute, Inc., Boston, MA (US);

Children's Medical Center Corporation, Boston, MA (US);

Inventors:

Kwok-Kin Wong, Arlington, MA (US);

Chunxiao Xu, Boston, MA (US);

Christine F. Brainson, Boston, MA (US);

Carla F. Kim, Boston, MA (US);

Glenn Dranoff, Lexington, MA (US);

Peter Hammerman, Newton, MA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6886 (2018.01); A61K 31/69 (2006.01); A61K 45/06 (2006.01); G01N 33/50 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); A61K 31/69 (2013.01); A61K 45/06 (2013.01); G01N 33/5011 (2013.01); G01N 33/57423 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/70596 (2013.01);
Abstract

The present invention is based on the identification of novel biomarkers predictive of responsiveness to anti-immune checkpoint inhibitor therapies.


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