Location History:
- Wilmington, DE (US) (2005 - 2012)
- Newark, DE (US) (2018)
- Landenberg, PA (US) (2019 - 2023)
Company Filing History:
6 out of 430 
1 out of 8,373 
1 out of 1,630 
Years Active: 2005-2023
Title: Joseph M. Fox: Innovator in Tetrazine Synthesis
Introduction
Joseph M. Fox is a prominent inventor based in Landenberg, Pennsylvania. He has made significant contributions to the field of chemistry, particularly in the synthesis of tetrazines. With a total of 7 patents to his name, Fox has established himself as a key figure in innovative chemical methodologies.
Latest Patents
Among his latest patents, Fox has developed reagents and methods for tetrazine synthesis. This patent discloses mono- and di-substituted tetrazines and methods for their preparation. It also includes a process for converting an oxetanyl ester to a thio-substituted tetrazine, which can then be transformed into a mono-substituted tetrazine, a di-substituted tetrazine, or a vinylether disubstituted tetrazine. Another notable patent involves methods for inducing bioorthogonal reactivity. This method catalytically converts a dihydrotetrazine into a tetrazine, utilizing an enzyme as a catalyst and an oxidant in the reaction medium.
Career Highlights
Joseph M. Fox has worked at prestigious institutions such as the University of Delaware and the Massachusetts Institute of Technology. His work at these institutions has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research.
Collaborations
Throughout his career, Fox has collaborated with talented individuals, including Yinzhi Fang and Yixin Xie. These collaborations have further enhanced his research and innovation in the field of chemistry.
Conclusion
Joseph M. Fox is a distinguished inventor whose work in tetrazine synthesis has made a significant impact in the field of chemistry. His innovative patents and collaborations reflect his commitment to advancing scientific knowledge and methodologies.