The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 29, 2020
Filed:
Dec. 15, 2016
Joseph Fox, Landenberg, PA (US);
Xinqiao Jia, Newark, DE (US);
Will Trout, Wilmington, DE (US);
Joel Rosenthal, Newark, DE (US);
Han Zhang, Columbia, MD (US);
Yinzhi Fang, Newark, DE (US);
Colin Thorpe, Newark, DE (US);
Shuang Liu, Newark, DE (US);
Yixin Xie, Newark, DE (US);
Joseph Fox, Landenberg, PA (US);
Xinqiao Jia, Newark, DE (US);
Will Trout, Wilmington, DE (US);
Joel Rosenthal, Newark, DE (US);
Han Zhang, Columbia, MD (US);
Yinzhi Fang, Newark, DE (US);
Colin Thorpe, Newark, DE (US);
Shuang Liu, Newark, DE (US);
Yixin Xie, Newark, DE (US);
UNIVERSITY OF DELAWARE, Newark, DE (US);
Abstract
A method for catalytically converting a dihydrotetrazine 1 into a tetrazine 2, wherein one R group on the dihydrotetrazine 1 is a substituted or unsubstituted aryl, heteroaryl, alkyl, alkenyl, alkynyl, carbonyl, or heteroatom-containing group, and the other R group is selected from the group consisting of H and substituted or unsubstituted aryl, heteroaryl, alkyl, alkenyl, alkynyl, carbonyl,- or heteroatom-containing groups; 1, 2 wherein the method comprises oxidizing dihydrotetrazine 1 in a reaction medium in the presence of a catalyst and a stoichiometric oxidant.