Location History:
- Basel, CH (2013)
- Lörrach, DE (2009 - 2015)
- Lorrach, DE (2015)
- Iorrach, DE (2015)
Company Filing History:
Years Active: 2009-2015
Title: Joerg Berghausen: Innovator in Pharmaceutical Chemistry
Introduction
Joerg Berghausen is a notable inventor in the field of pharmaceutical chemistry, recognized for his contributions to the development of innovative treatments. He is based in Lörrach, Germany, and has been awarded a total of seven patents throughout his career. His work primarily focuses on inhibitors that target critical interactions in cancer biology.
Latest Patents
Among his latest patents is a crystalline form of an inhibitor of MDM2/4 and p53 interaction. This invention, specifically a crystalline form of (S)-1-(4-Chloro-phenyl)-7-isopropoxy-6-methoxy-2-(4-{methyl-[4-(4-methyl-3-oxo-piperazin-1-yl)-trans-cyclohexylmethyl]-amino}-phenyl)-1,4-dihydro-2H-isoquinolin-3-one, is significant for its potential in treating diseases associated with the interaction between p53 and MDM2/MDM4. Additionally, he has developed crystalline forms of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea and its salts