The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 14, 2013

Filed:

Dec. 20, 2010
Applicants:

Joerg Berghausen, Basel, CH;

Nicole Buschmann, Basel, CH;

Pascal Furet, Basel, CH;

François Gessier, Basel, CH;

Joanna Hergovich Lisztwan, Basel, CH;

Philipp Holzer, Basel, CH;

Edgar Jacoby, Basel, CH;

Joerg Kallen, Basel, CH;

Keiichi Masuya, Basel, CH;

Carole Pissot Soldermann, Basel, CH;

Haixia Ren, Shanghai, CN;

Stefan Stutz, Basel, CH;

Inventors:

Joerg Berghausen, Basel, CH;

Nicole Buschmann, Basel, CH;

Pascal Furet, Basel, CH;

François Gessier, Basel, CH;

Joanna Hergovich Lisztwan, Basel, CH;

Philipp Holzer, Basel, CH;

Edgar Jacoby, Basel, CH;

Joerg Kallen, Basel, CH;

Keiichi Masuya, Basel, CH;

Carole Pissot Soldermann, Basel, CH;

Haixia Ren, Shanghai, CN;

Stefan Stutz, Basel, CH;

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 37/18 (2006.01); A61K 31/65 (2006.01); C07D 215/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to substituted nitrogen containing bicyclic heterocycles of the formula (I) wherein Z is CHor N—Rand X, R, R, R, R, Rand n are as defined in the description. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of MDM2 and/or MDM4, or variants thereof.


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