Location History:
- Slough Berkshire, GB (2020)
- Slough, GB (2020 - 2024)
Company Filing History:
9 out of 109 
2 out of 1,451 
Years Active: 2020-2024
Title: Innovations and Contributions of James Philip O'Connell
Introduction
James Philip O'Connell is a notable inventor based in Slough, GB. He has made significant contributions to the field of biotechnology, particularly in the development of therapeutic antibodies. With a total of nine patents to his name, O'Connell's work has the potential to impact various medical treatments.
Latest Patents
O'Connell's latest patents include innovative methods related to anti-TNFα antibodies. One of his patents demonstrates that certain compounds can bind to TNF and stabilize a conformation of trimeric TNF that binds to the TNF receptor. This discovery allows for the development of antibodies that selectively bind to complexes of these compounds with TNF superfamily members. These antibodies may be utilized to detect further compounds with similar activity and serve as target engagement biomarkers. Another significant patent involves a method for identifying potential inhibitors of APO TNFα trimers. This patent discloses a new, stable trimeric TNFα structure with distorted symmetry that can bind to the TNFR1 receptor, attenuating signaling and potentially aiding in the treatment and prevention of diseases associated with the soluble TNFα/TNFR1 interaction.
Career Highlights
Throughout his career, O'Connell has worked with prominent companies in the pharmaceutical industry, including UCB Biopharma and Sanofi. His experience in these organizations has allowed him to collaborate on groundbreaking research and development projects.
Collaborations
O'Connell has collaborated with esteemed colleagues such as John Robert Porter and Alastair Lawson. These partnerships have contributed to the advancement of his research and the successful development of his patents.
Conclusion
James Philip O'Connell's innovative work in the field of biotechnology, particularly in the area of therapeutic antibodies, showcases his significant contributions to medical science. His patents reflect a commitment to advancing treatment options for various diseases, highlighting the importance of his research in the ongoing quest for medical breakthroughs.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.