The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 16, 2021
Filed:
Dec. 13, 2017
Applicants:
Ucb Biopharma Srl, Brussels, BE;
Sanofi, Paris, FR;
Inventors:
Alastair David Griffiths Lawson, Slough, GB;
Daniel John Lightwood, Slough, GB;
Rebecca Jayne Munro, Slough, GB;
James Philip O'Connell, Slough, GB;
John Robert Porter, Slough, GB;
Assignees:
UCB BIOPHARMA SRL, Brussels, BE;
SANOFI, Paris, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/24 (2006.01);
U.S. Cl.
CPC ...
C07K 16/241 (2013.01); C07K 2317/32 (2013.01); C07K 2317/34 (2013.01); C07K 2317/55 (2013.01); C07K 2317/92 (2013.01);
Abstract
It has been demonstrated that certain compounds bind to TNF and stabilise a conformation of trimeric TNF that binds to the TNF receptor. Antibodies which selectively bind to complexes of such compounds with TNF superfamily members are disclosed. These antibodies may be used to detect further compounds with the same activity, and as target engagement biomarker.