The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 05, 2021

Filed:

Oct. 22, 2015
Applicant:

Ucb Biopharma Srl, Brussels, BE;

Inventors:

James Philip O'Connell, Slough, GB;

John Robert Porter, Slough, GB;

Alastair Lawson, Slough, GB;

Boris Kroeplien, Slough, GB;

Stephen Edward Rapecki, Slough, GB;

Timothy John Norman, Slough, GB;

David James McMillan, Slough, GB;

Graham John Warrellow, Slough, GB;

Daniel Christopher Brookings, Slough, GB;

Rikki Peter Alexander, Slough, GB;

Assignee:

UCB BIOPHARMA SRL, Brussels, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); C07K 14/525 (2006.01); C07K 14/705 (2006.01); C07K 16/24 (2006.01); C07D 401/14 (2006.01); C07D 471/00 (2006.01); C07D 213/72 (2006.01); C07D 235/04 (2006.01); C07D 239/26 (2006.01); C07D 471/04 (2006.01); A61K 47/64 (2017.01); A61P 37/00 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6845 (2013.01); A61K 47/6425 (2017.08); A61P 35/00 (2018.01); A61P 37/00 (2018.01); C07D 213/72 (2013.01); C07D 235/04 (2013.01); C07D 239/26 (2013.01); C07D 401/14 (2013.01); C07D 471/00 (2013.01); C07D 471/04 (2013.01); C07K 14/525 (2013.01); C07K 14/70575 (2013.01); C07K 16/241 (2013.01); G01N 33/6854 (2013.01); G01N 33/6863 (2013.01); C07K 2317/55 (2013.01); C07K 2317/92 (2013.01); G01N 2333/525 (2013.01); G01N 2500/02 (2013.01);
Abstract

The invention is in the field of TNF signalling. Compounds have been identified which are capable of modulating signalling of TNF trimers through receptors. Methods of identifying such compounds are therefore provided. The compounds themselves have utility in therapy.


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