This inventor holds 11 USPTO granted patents and 2 published patent applications. Top assignee: Research Foundation for Mental Hygiene, Inc.. Active years: 2012-2019.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2012-2019
Title: Inge Grundke-Iqbal: Pioneering Research in Neurodegenerative Diseases
Introduction
Inge Grundke-Iqbal is a prominent inventor based in Staten Island, NY (US). She has made significant contributions to the field of neurodegenerative diseases, particularly in the treatment of tauopathies. With a total of 11 patents to her name, her work has been instrumental in advancing therapeutic approaches for conditions such as Alzheimer's disease.
Latest Patents
One of her latest patents focuses on the treatment of tauopathies through passive immunization targeting the N-terminal projection domain of tau. This method involves administering antibodies specific to the amino terminal region of human tau, which can reduce total tau levels, decrease tau hyperphosphorylation, and improve reference memory. The effectiveness of this approach was demonstrated in aged 3×Tg-AD mice, a widely accepted model for Alzheimer's disease and frontotemporal dementia in humans. Another notable patent involves neurogenic brain-derived neurotrophic factor peptides. These five tetra peptides correspond to different active regions of brain-derived neurotrophic factor (BDNF) and can modulate BDNF signaling in a partial agonist/antagonist manner. This therapeutic approach offers potential benefits for neural pathologies where BDNF levels are dysregulated.
Career Highlights
Inge Grundke-Iqbal is associated with the Research Foundation for Mental Hygiene, Inc., where she continues her groundbreaking research. Her work has garnered attention and respect within the scientific community, contributing to a deeper understanding of neurodegenerative diseases.
Collaborations
She has collaborated with notable colleagues, including Khalid Iqbal and Herbert Mossler, further enhancing the impact of her research through teamwork and shared expertise.
Conclusion
Inge Grundke-Iqbal's innovative work in the field of neurodegenerative diseases exemplifies the importance of research in developing effective treatments. Her contributions continue to pave the way for advancements in understanding and addressing these complex conditions.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile