The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2014

Filed:

Nov. 12, 2012
Applicant:

The Research Foundation for Mental Hygiene, Inc., Menands, NY (US);

Inventors:

Khalid Iqbal, Staten Island, NY (US);

Inge Grundke-Iqbal, Staten Island, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 37/18 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a neurotrophic peptide having an amino acid sequence of VGDGGLFEKKL (SEQ ID NO:1) and alternatively comprising an adamantyl group at the C- and/or N-terminal end. The neurotrophic peptide can rescue cognition, correct impairments in neural cell proliferation and synaptic plasticity, and thus address the cognitive defects associated with Down syndrome.


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