The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2016
Filed:
Jul. 08, 2014
Applicant:
The Research Foundation for Mental Hygiene, Inc., Menands, NY (US);
Inventors:
Khalid Iqbal, Staten Island, NY (US);
Inge Grundke-Iqbal, Staten Island, NY (US);
Assignee:
The Research Foundation For Mental Hygiene, Inc., Menands, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
A01N 37/18 (2006.01); A61K 38/16 (2006.01); C07K 14/475 (2006.01); A61K 38/08 (2006.01); A61K 38/18 (2006.01); C07K 5/103 (2006.01); C07K 5/113 (2006.01); C07K 7/06 (2006.01);
U.S. Cl.
CPC ...
C07K 14/475 (2013.01); A61K 38/08 (2013.01); A61K 38/185 (2013.01); C07K 5/101 (2013.01); C07K 5/1008 (2013.01); C07K 5/1021 (2013.01); C07K 7/06 (2013.01);
Abstract
A neurotrophic peptide having the sequence VGDGGLFEKKL (SEQ ID NO: 1) may be used to help sustain local microenvironment after mild-to-moderate brain injury. Treatment with the peptide was shown to enhance differentiation of newly born progenitors in the dentate gyrus 30 days after injury and to promote neuronal maturation and survival that is not seen naturally after traumatic brain injuries.