The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 22, 2017
Filed:
Nov. 24, 2015
Applicant:
The Research Foundation for Mental Hygiene, Inc., Menands, NY (US);
Inventors:
Khalid Iqbal, Staten Island, NY (US);
Inge Grundke-Iqbal, Staten Island, NY (US);
Assignee:
The Research Foundation for Mental Hygiene, Inc., Menands, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A01N 37/18 (2006.01); A61K 38/18 (2006.01);
U.S. Cl.
CPC ...
A61K 38/185 (2013.01);
Abstract
A method of treating autism spectrum disorders using a therapeutic amount of a synthetic amino acid sequence corresponding to a portion of human ciliary neurotrophic factor (CNTF). In particular, the synthetic amino acid sequence is VGDGGLFEKKL (SEQ ID NO: 1), referred to as Peptide 6. Peptide 6 was tested and shown to exert a neuroprotective effect by modulating CNTF/JAK/STAT pathway and LIF signaling and enhancing brain derived neurotrophic factor (BDNF) expression.