The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 08, 2013
Filed:
Apr. 23, 2010
Applicants:
Khalid Iqbal, Staten Island, NY (US);
Sonia Chalbot, New York, NY (US);
Inge Grundke-iqbal, Staten Island, NY (US);
Inventors:
Khalid Iqbal, Staten Island, NY (US);
Sonia Chalbot, New York, NY (US);
Inge Grundke-Iqbal, Staten Island, NY (US);
Assignee:
Research Foundation For Mental Hygiene, Inc., Menands, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/34 (2006.01);
U.S. Cl.
CPC ...
Abstract
A system and method for evaluating blood-neural barrier permeability. Phospholipid liposomes are labeled with a fluorescent phospholipase A2 substrate and exposed to cerebrospinal fluid. The change in fluorescence is monitored to determine PLA2 activity. The PLA2 activity is used to evaluate the permeability and function of the blood-neural barrier.