Ian Johnston

Title: Ian Johnston: Innovator in Chimeric Antigen Receptors

Introduction

Ian Johnston is a notable inventor based in Rosrath, Germany. He has made significant contributions to the field of biotechnology, particularly in the development of chimeric antigen receptors (CARs). With a total of four patents to his name, Johnston's work has the potential to impact therapeutic strategies in immunology.

Latest Patents

Among his latest patents is a chimeric antigen receptor that includes an antigen binding domain specific for a target antigen, a spacer comprising C2-set Ig-like domains, a transmembrane domain, and an intracellular signaling domain. This innovative CAR design aims to enhance the efficacy of immune responses against specific antigens. Another significant patent involves a packaging cell line for the production of VSV-G pseudotyped retroviral vector particles, which are crucial for gene therapy applications. This invention utilizes a cell line that is negative for Low-Density Lipoprotein Receptor (LDLR) and stably expresses VSV-G, facilitating the production of viral particles.

Career Highlights

Ian Johnston has worked with prominent companies in the biotechnology sector, including Miltenyi Biotec GmbH and Miltenyi Biotec B.V. & Co. KG. His experience in these organizations has allowed him to collaborate on cutting-edge research and development projects.

Collaborations

Johnston has collaborated with notable colleagues such as Andrew Kaiser and Mario Assenmacher. These partnerships have contributed to the advancement of his research and the successful development of his patented technologies.

Conclusion

Ian Johnston's innovative work in the field of chimeric antigen receptors and viral vector production showcases his commitment to advancing biotechnology. His contributions are poised to make a lasting impact on therapeutic approaches in immunology and gene therapy.