The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 2025
Filed:
Aug. 28, 2019
Applicant:
Miltenyi Biotec B.v. & Co. KG, Bergisch Gladbach, DE;
Inventors:
Thomas Schaser, Rösrath, DE;
Johann-Christoph Dettmann, Bergisch Gladbach, DE;
Martin Meyer, Kürten, DE;
Ian Johnston, Rösrath, DE;
Assignee:
MILTENYI BIOTEC B.V. & CO. KG, Bergisch Gladbach, DE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2005.12); C12N 7/00 (2005.12);
U.S. Cl.
CPC ...
C12N 15/86 (2012.12); C12N 7/00 (2012.12); C12N 2740/15023 (2012.12); C12N 2740/15043 (2012.12); C12N 2740/15052 (2012.12); C12N 2810/6081 (2012.12);
Abstract
The present invention provides the use of a packaging cell line for the production of VSV-G pseudotyped retroviral vector particles or virus like particles thereof, wherein said packaging cell line is negative for Low-Density Lipoprotein Receptor (LDLR), optionally said packaging cell line stably expresses VSV-G. A method for producing said VSV-G pseudotyped retroviral vector particles or virus like particles thereof is disclosed as well as said particles obtained by said method.