Company Filing History:
Years Active: 2020-2024
Title: The Innovative Contributions of Han-Yu Chuang
Introduction
Han-Yu Chuang is a prominent inventor based in San Diego, CA. He has made significant contributions to the field of biotechnology, particularly in the area of cancer detection and sequencing technologies. With a total of 8 patents to his name, Chuang's work has advanced the methodologies used in genetic analysis and diagnostics.
Latest Patents
Chuang's latest patents include groundbreaking methods for detecting tumor-associated variants through the analysis of cell-free DNA (cfDNA) fragment sizes. His first patent focuses on improving the specificity and sensitivity of assays by synergistically combining size and sequence information from cfDNA fragments obtained from test samples. This innovative approach enhances the detection of variants of interest, which is crucial for effective cancer diagnosis and treatment.
Another notable patent involves the use of universal short adapters with variable-length non-random unique molecular identifiers (UMIs). This invention provides methods and systems for determining sequences of interest using UMIs that can be uniquely associated with individual polynucleotide fragments. This technology is particularly beneficial for analyzing sequences with low allele frequencies or long sequence lengths, thereby expanding the capabilities of genetic sequencing.
Career Highlights
Chuang is currently employed at Illumina Corporation, a leading company in the field of genomics. His work at Illumina has positioned him at the forefront of innovative research and development in DNA sequencing technologies. His contributions have not only advanced scientific understanding but have also paved the way for new diagnostic tools in medicine.
Collaborations
Throughout his career, Han-Yu Chuang has collaborated with notable colleagues, including Chen Zhao and Kevin Eric Wu. These collaborations have fostered a dynamic research environment that encourages the exchange of ideas and the development of cutting-edge technologies.
Conclusion
Han-Yu Chuang's innovative work in biotechnology and his numerous patents highlight his significant impact on the field of genetic analysis. His contributions continue to shape the future of cancer detection and sequencing technologies, making him a key figure in the scientific community.