The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 03, 2020
Filed:
Oct. 05, 2016
Applicant:
Illumina, Inc., San Diego, CA (US);
Inventors:
Li Teng, San Diego, CA (US);
Chia-Ling Hsieh, San Diego, CA (US);
Charles Lin, San Diego, CA (US);
Han-Yu Chuang, San Diego, CA (US);
Assignee:
ILLUMINA, INC., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C07H 21/00 (2006.01); C12Q 1/6806 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6806 (2013.01); C12Q 1/6806 (2013.01); C12Q 2535/122 (2013.01); C12Q 2537/159 (2013.01); C12Q 2537/163 (2013.01); C12Q 2563/131 (2013.01);
Abstract
Presented herein are methods and compositions for enhancing specific enrichment of target sequences in a nucleic acid library. Off-target hybridization probes may be used to reduce binding and/or capture of off-target regions of a nucleic acid library in a targeted sequencing workflow. The off-target hybridization probes may be specific for locations known to generate off-target sequencing reads for a particular set of hybridization probes.