Company Filing History:
Years Active: 2012-2025
Title: Guanghui Ma: Innovator in Vaccine Development
Introduction
Guanghui Ma is a prominent inventor based in Beijing, China. He has made significant contributions to the field of vaccine development, holding a total of 7 patents. His innovative work focuses on creating advanced vaccine formulations and methodologies.
Latest Patents
One of his latest patents is a microcapsule-based vaccine. This vaccine comprises an antigen and a matrix of biodegradable polymer blend. The polymer blend includes a hydrophobic polymer and an amphiphilic block copolymer. The vaccine exists in the form of microcapsules that feature a multi-cavity structure inside. It has an average particle diameter of preferably 10-100 μm and more preferably 30-60 μm. The preparation method involves making porous microspheres from the polymer blend, mixing these microspheres with an antigen-containing solution, and sealing the openings of the porous microspheres to form an opening-sealed microcapsule loaded with the antigen. Another notable patent is related to the method of making exosomes from tumor cell/antigen presenting cell hybrid cells. This exosome is secreted by a hybrid cell formed by antigen-presenting cells phagocytosing the cell nuclei of tumor cells. This innovative strategy allows for endogenous expression of tumor antigens on macrophages, resulting in exosomes that possess excellent targeting capabilities to lymph nodes and tumors.
Career Highlights
Guanghui Ma has worked with esteemed institutions such as the Chinese Academy of Sciences and the Institute of Process Engineering, Chinese Academy of Sciences. His work in these organizations has significantly advanced the field of vaccine research and development.
Collaborations
He has collaborated with notable colleagues, including Zhiguo Su and Wei Wei. Their joint efforts have contributed to the success of various research projects and innovations in vaccine technology.
Conclusion
Guanghui Ma is a distinguished inventor whose work in vaccine development has led to several important patents. His innovative approaches and collaborations continue to impact the field positively.