The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 26, 2025

Filed:

Aug. 16, 2019
Applicant:

Institute of Process Engineering, Chinese Academy of Sciences, Beijing, CN;

Inventors:

Guanghui Ma, Beijing, CN;

Wei Wei, Beijing, CN;

Xiaobo Xi, Beijing, CN;

Tong Ye, Beijing, CN;

Xiangming Na, Beijing, CN;

Shuang Qing, Beijing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/29 (2006.01); A61K 9/50 (2006.01); A61K 39/00 (2006.01); A61K 39/39 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/29 (2013.01); A61K 9/5031 (2013.01); A61K 39/0011 (2013.01); A61K 39/00117 (2018.08); A61K 39/39 (2013.01); A61P 35/00 (2018.01); A61K 2039/55561 (2013.01); A61K 2039/55572 (2013.01); A61K 2039/6093 (2013.01);
Abstract

A vaccine comprising antigen and a matrix of biodegradable polymer blend, wherein the polymer blend comprises hydrophobic polymer and amphiphilic block copolymer, and the vaccine exists in form of microcapsules that comprise a multi-cavity structure inside, and has an average particle diameter of preferably 10-100 μm and more preferably 30-60 μm, and is prepared by means of the following method: making porous microspheres from the polymer blend, then mixing the porous microspheres with antigen-containing solution, and then sealing openings of porous microspheres that have been loaded with the antigen-containing solution to form an opening-sealed microcapsule loaded with the antigen.


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