Company Filing History:

12 out of 349

Research Triangle Institute

patents

1 out of 8,684

US Government As Represented by the Secretary of the Army

patents

3 out of 832,718

Other

patents

Years Active: 1990-2006

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16 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 7071204 - Camptothecin analogs having an E-ring ketone (2006-07-04),

2. 7067666 - 7-substituted camptothecin and camptothecin analogs and methods for producing the same (2006-06-27),

3. 6825206 - Camptothecin compounds with a thioether group (2004-11-30),

4. 6288072 - Camptothecin &bgr;-alanine esters with topoisomerase I inhibition (2001-09-11),

5. 6268375 - 10, 11-difluoromethylenedioxycamptothecin compounds with topoisomerase I inhibition (2001-07-31),

6. 5401747 - Alkyl camptothecin compounds as potent inhibitors of human colorectal (1995-03-28),

7. 5364858 - Camptothecin analogs as potent inhibitors of topoisomerase I (1994-11-15),

8. 5340817 - Method of treating tumors with anti-tumor effective camptothecin (1994-08-23),

9. 5244903 - Camptothecin analogs as potent inhibitors of topoisomerase I (1993-09-14),

10. 5227380 - Pharmaceutical compositions and methods employing camptothecins (1993-07-13),

11. 5204352 - Compounds exhibiting anti-parasitic activity and a method for their use (1993-04-20),

12. 5180722 - 10,11-methylenedioxy-20(RS)-camptothecin and (1993-01-19),

13. 5122526 - Camptothecin and analogs thereof and pharmaceutical compositions and (1992-06-16),

14. 5049668 - 10,11-methylenedioxy-20(RS)-camptothecin analogs (1991-09-17),

15. 4981968 - Synthesis of camptothecin and analogs thereof (1991-01-01),

Title: Innovations of Govindarajan Manikumar

Introduction

Govindarajan Manikumar is a prominent inventor based in Raleigh, NC (US). He has made significant contributions to the field of anti-tumor compounds, holding a total of 16 patents. His work focuses on developing effective treatments for cancer through innovative chemical compounds.

Latest Patents

One of his latest patents is for Camptothecin analogs having an E-ring ketone. These compounds are recognized as effective anti-tumor agents, as they inhibit the enzyme topoisomerase I and may alkylate DNA within the associated topoisomerase I DNA cleavable complex. Another notable patent involves 7-substituted camptothecin and methods for producing these compounds. This patent also emphasizes the effectiveness of these camptothecin compounds as anti-tumor agents, highlighting their ability to inhibit topoisomerase I and interact with DNA.

Career Highlights

Throughout his career, Govindarajan has worked with various organizations, including the Research Triangle Institute. His innovative research has led to advancements in cancer treatment, showcasing his dedication to improving healthcare through scientific discovery.

Collaborations

Govindarajan has collaborated with notable figures in the field, including Mansukh C. Wani and Monroe E. Wall. These partnerships have contributed to the development of groundbreaking anti-tumor compounds.

Conclusion

Govindarajan Manikumar's contributions to the field of anti-tumor research through his patents and collaborations highlight his role as a significant inventor. His work continues to impact cancer treatment and showcases the importance of innovation in medicine.

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1 patent (EPO):

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Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.