The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 20, 1993
Filed:
Sep. 29, 1987
Richard J Sundberg, Charlottesville, VA (US);
Daniel J Dahlhausen, Columbus, OH (US);
Govindarajan Manikumar, Raleigh, NC (US);
Babu J Mavunkel, Baltimore, MD (US);
Hikmat A Musallam, Damascus, MD (US);
Atanu Biswas, Cleveland, OH (US);
Srinivasan Varadarajan, Stow, OH (US);
The United States of America as represented by the Secretary of the Army, Washington, DC (US);
Abstract
Novel compounds are provided which exhibit high levels of anti-parasitic activity, specifically against parasites of the genus Trypanosoma. The compounds are comprised of aryl-substituted quaternary heteroaromatic salts which include a positively charged imidazolium or other heterocyclic ring, a linking group, a phenyl ring, and a polar functional group. The polar functional group is preferably a quanylhydrazone or a heterocyclic hydrazone. A method is also provided for treating the diseases associated with Trypanosoma parasites which comprises administering to infected animals or humans an effective amount of a compound of the present invention.