Redwood City, CA, United States of America

Gjalt W Huisman

This inventor holds 134 USPTO granted patents and 22 published patent applications and 15 EPO patents, primarily in Enzyme Engineering (CPC class Y02P20-52). Top assignees: Codexis, Inc., Metabolix, Inc., Crosswalk Therapeutics, Inc.. Active years: 2001-2025.

IDiyas Innovation Intelligence. (2026). Inventor Profile: Gjalt W Huisman. Retrieved from https://idiyas.com/inventor/gjalt-w-huisman

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

USPTO Granted Patents = 134 (Patent Applications = 22)

% Patents Active = 85.1

EPO Patents = 15 (Patent Applications = 18)

Average Co-Inventor Count = 5.6

ph-index = 22

Forward Citations = 1,830(Granted Patents)

Forward Citations (Not Self Cited) = 1,191(Dec 10, 2025)

Inventors with similar research interests:

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Location History:

Boston, MA (US) (2001)
San Carlos, CA (US) (2003 - 2015)
Redwood City, CA (US) (2015 - 2024)

Company Filing History:

Crosswalk Therapeutics, Inc.

Codexis Mayflower Holdings, LLC

where one patent can have more than one assignee

Years Active: 2001-2025

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Areas of Expertise:

Alpha-Galactosidase Variants

Ketoreductase Polypeptides

Imine Reductases

Methionine Gamma Lyase

Phenylalanine Ammonia Lyase

T7 RNA Polymerase

Automated Screening

Polynucleotides Encoding

Engineered Variants

Enone Reductases

Tyrosine Ammonia Lyase

134 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 12497605 - Engineered acid alpha-glucosidase variants (2025-12-16),

2. 12421532 - Polynucleotides encoding engineered imine reductases (2025-09-23),

3. 12415990 - Ketoreductase polypeptides for the reduction of acetophenones (2025-09-16),

4. 12378585 - Ketoreductase polypeptides for the production of (R)-3-hydroxythiolane (2025-08-05),

5. 12371674 - Enone reductases (2025-07-29),

6. 12365927 - Engineered ketoreductase polypeptides (2025-07-22),

7. 12286655 - Human alpha-galactosidase variants (2025-04-29),

8. 12263207 - Human alpha-galactosidase variants (2025-04-01),

9. 12257291 - Human alpha-galactosidase variants (2025-03-25),

10. 12129494 - T7 RNA polymerase variants (2024-10-29),

11. 12110521 - Engineered methionine gamma lyase variants (2024-10-08),

12. 11970722 - Engineered acid alpha-glucosidase variants (2024-04-30),

13. 11965194 - Ketoreductase polypeptides for the production of (R)-3-hydroxythiolane (2024-04-23),

14. 11913045 - Engineered phenylalanine ammonia lyase polypeptides (2024-02-27),

15. 11618911 - Engineered imine reductases and methods for the reductive amination of ketone and amine compounds (2023-04-04),

Title: The Innovative Mind of Gjalt W Huisman

Introduction: Gjalt W Huisman is a prolific inventor based in Redwood City, CA, with an impressive portfolio of 123 patents to his name. His groundbreaking work in the field of biotechnology has led to the development of novel enzymes and therapies that have the potential to revolutionize various industries.

Latest Patents: Among his latest inventions are engineered acid alpha-glucosidase variants, designed to enhance expression, stability, and activity in cell lysates. Additionally, Gjalt W Huisman's ketoreductase polypeptides for the production of (R)-3-hydroxythiolane offer improved properties over naturally occurring enzymes, enabling the synthesis of valuable chiral compounds.

Career Highlights: Gjalt W Huisman has made significant contributions to companies such as Codexis, Inc., and Metabolix, Inc., where his expertise in enzyme engineering and biocatalysis has been instrumental in driving innovation and pushing the boundaries of what is possible in biotechnology.

Collaborations: Throughout his career, Gjalt W Huisman has collaborated with esteemed colleagues such as Emily Mundorff and Nicholas John Agard, pooling their collective knowledge and expertise to tackle complex challenges and achieve groundbreaking results in the field of biotechnology.

Conclusion: Gjalt W Huisman's relentless pursuit of innovation and his passion for pushing the boundaries of biotechnology have cemented his reputation as a visionary inventor. His patented inventions are a testament to his creativity, ingenuity, and unwavering commitment to advancing scientific knowledge and improving the world we live in.

Profile summary based on public USPTO records.