The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2024
Filed:
Dec. 21, 2021
Codexis, Inc., Redwood City, CA (US);
Mathew G. Miller, San Carlos, CA (US);
Chinping Chng, Menlo Park, CA (US);
Oscar Alvizo, Fremont, CA (US);
Melissa Ann Mayo, Foster City, CA (US);
James Nicholas Riggins, San Francisco, CA (US);
Xiang Yi, San Carlos, CA (US);
Jonathan S. Penfield, Truckee, CA (US);
Gjalt W. Huisman, Redwood City, CA (US);
Jared Davis, Cheshire, CT (US);
Yasushi Saotome, Solana Beach, CA (US);
Codexis, Inc., Redwood City, CA (US);
Abstract
The present invention provides engineered RNA polymerase variants and compositions comprising these variants. The present invention further provides engineered T7 RNA polymerase variants and compositions comprising these variants. These variants have been evolved for selective incorporation of the m7G(5')ppp(5′)m7G cap analog over GTP at the initiation of in vitro transcription. The present invention also provides methods for selective capping of RNA transcripts.