The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 08, 2024
Filed:
May. 19, 2022
Syntis Bio, Inc., Boston, MA (US);
Kierra Aleece Franklin, Dolton, IL (US);
Stephanie Sue Galanie, Knoxville, TN (US);
Gjalt W. Huisman, Redwood City, CA (US);
Nikki D. Kruse, San Carlos, CA (US);
Kerryn McCluskie, Pacifica, CA (US);
Vesna Mitchell, Santa Clara, CA (US);
Leann Quertinmont Teadt, Redwood City, CA (US);
Kristen Jean Vallieu, Las Vegas, NV (US);
SYNTIS BIO, INC., Boston, MA (US);
Abstract
The present invention provides engineered methionine gamma lyase polypeptides and compositions thereof. The engineered methionine gamma lyase polypeptides have been optimized to provide improved thermostability, protease stability, and stability under a range of pH conditions, including acidic (pH<7) conditions. The present invention also relates to the use of the compositions comprising the engineered methionine gamma lyase polypeptides for therapeutic purposes.