Santa Clara, CA, United States of America

Vesna Mitchell

This inventor holds 54 USPTO granted patents and 18 published patent applications, plus 2 CIPO patents and 9 EPO patents, primarily in Engineered Enzymes. Top assignees: Codexis, Inc., Syntis Bio, Inc.. Active years: 2012-2025.

USPTO Granted Patents = 54 (Patent Applications = 18)

% Patents Active = 96.3

CIPO Patents = 2 (Patent Applications = 9)

EPO Patents = 9 (Patent Applications = 23)

Average Co-Inventor Count = 6.3

ph-index = 5

Forward Citations = 258(Granted Patents)

Forward Citations (Not Self Cited) = 142(Dec 10, 2025)

Location History:

San Jose, CA (US) (2012 - 2017)
Santa Clara, CA (US) (2017 - 2024)

Company Filing History:

Years Active: 2012-2025

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Areas of Expertise:

P450-BM3 Variants

Carboxyesterase Polypeptides

Ketoreductase Polypeptides

Engineered DNA Polymerase

Enone Reductases

Engineered Phosphopentomutase

Methionine Gamma Lyase

Purine Nucleoside Phosphorylase

Penicillin-G Acylases

Endoglucanase Variants

Phenylalanine Ammonia Lyase

54 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 12421509 - Engineered phosphopentomutase variant enzymes (2025-09-23),

2. 12371674 - Enone reductases (2025-07-29),

3. 12365882 - P450-BM3 variants with improved activity (2025-07-22),

4. 12286653 - Carboxyesterase polypeptides for amide coupling (2025-04-29),

5. 12252723 - Ketoreductase polypeptides and polynucleotides (2025-03-18),

6. 12129495 - Engineered DNA polymerase variants (2024-10-29),

7. 12110521 - Engineered methionine gamma lyase variants (2024-10-08),

8. 12110493 - Engineered purine nucleoside phosphorylase variant enzymes (2024-10-08),

9. 12084697 - Penicillin-G acylases (2024-09-10),

10. 12018295 - Engineered DNA polymerase variants (2024-06-25),

11. 11965192 - Penicillin-G acylases (2024-04-23),

12. 11807874 - P450-BM3 variants with improved activity (2023-11-07),

13. 11795445 - Engineered phosphopentomutase variant enzymes (2023-10-24),

14. 11746369 - Ketoreductase polypeptides and polynucleotides (2023-09-05),

15. 11591588 - Penicillin-G acylases (2023-02-28),

Title: The Innovative Contributions of Vesna Mitchell in Biotechnology

Introduction: Vesna Mitchell, based in Santa Clara, CA, is a prominent inventor with an impressive portfolio of 49 patents. Her work primarily focuses on engineered DNA polymerase variants and methionine gamma lyase variants, demonstrating her significant contributions to the field of biotechnology.

Latest Patents: Two of her latest patents include the development of engineered DNA polymerase variants. This innovation relates to engineered DNA polymerase polypeptides and compositions, along with polynucleotides encoding these polypeptides. The patent also outlines methods for using these engineered variants for diagnostic and other applications. Additionally, she has developed engineered methionine gamma lyase variants that improve thermostability, protease stability, and performance under various pH conditions, including acidic environments. The therapeutic uses of these compositions highlight the potential impact of her work.

Career Highlights: Throughout her career, Vesna has been associated with notable companies such as Codexis, Inc. and Syntis Bio, Inc. These roles have allowed her to push the boundaries of research in biotechnology and contribute to groundbreaking innovations.

Collaborations: Vesna has collaborated with other talented scientists in her field, including Xiyun Zhang and Jeffrey C. Moore. These partnerships have fostered a collaborative environment that promotes creativity and the development of advanced biotechnological solutions.

Conclusion: Vesna Mitchell’s vast experience and innovative spirit have led to substantial contributions in the biotechnology sector. Her patents reflect her dedication to enhancing scientific understanding and developing practical applications that could revolutionize diagnostics and therapeutics in healthcare.