Location History:
- West Newton, MA (US) (2001)
- W. Newtown, MA (US) (2001)
- W. Newton, MA (US) (2002 - 2008)
- Newton, MA (US) (2001 - 2023)
Company Filing History:
4 out of 12 
3 out of 12 
1 out of 38 
Years Active: 2001-2023
Title: Innovations of Ezra Solomon Abrams
Introduction
Ezra Solomon Abrams is a notable inventor based in Newton, MA (US). He has made significant contributions to the field of biotechnology, particularly in the area of nucleic acid processing. With a total of 10 patents to his name, Abrams has developed innovative methods and systems that enhance the efficiency of genomic DNA purification and automated nucleic acid processing.
Latest Patents
One of Abrams' latest patents is titled "Preparative electrophoretic method for targeted purification of genomic DNA fragments." This invention involves a sample containing high-molecular-weight (HMW) DNA that is entrapped in a gel matrix. The gel matrix is treated with a lysis reagent to release the HMW DNA from the particles. The method allows for the purification of HMW DNA by applying an electrophoretic field, which effectively removes the DNA from the particles and other sample constituents. Additionally, the gel matrix can be treated with DNA cleavase reagents to liberate defined segments of the DNA as smaller fragments. The electrophoretically separated DNA fragments can then be isolated from the gel matrix.
Another significant patent by Abrams is focused on "Apparatuses, methods and systems for automated processing of nucleic acids and electrophoretic sample preparation." This invention presents methods and systems for the automated extraction, purification, and processing of nucleic acids from biological samples. Hydrogel supports are utilized to immobilize biological input samples, facilitating the extraction of nucleic acids during operations. This innovation enhances the automation of sample processing on robotic liquid handling systems.
Career Highlights
Throughout his career, Ezra Solomon Abrams has worked with several companies, including Sage Science, Inc. and Mosaic Technologies Inc. His work has been instrumental in advancing technologies related to nucleic acid processing and purification.
Collaborations
Abrams has collaborated with notable individuals in his field, including T Christian Boles and Todd J Barbera. These collaborations have contributed to the development of innovative solutions in biotechnology.
Conclusion
Ezra Solomon Abrams is a distinguished inventor whose work has significantly impacted the field of biotechnology. His innovative patents and contributions to automated nucleic acid processing continue to advance scientific research and applications.