The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2015
Filed:
Aug. 03, 2012
Applicants:
T. Christian Boles, Bedford, MA (US);
Ezra Solomon Abrams, Newton, MA (US);
Inventors:
T. Christian Boles, Bedford, MA (US);
Ezra Solomon Abrams, Newton, MA (US);
Assignee:
Sage Science, Inc., Beverly, MA (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); C12N 15/10 (2006.01); C40B 50/06 (2006.01); C12M 1/00 (2006.01); C12P 19/34 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1003 (2013.01); B01L 3/502715 (2013.01); B01L 3/502776 (2013.01); C12N 15/102 (2013.01); C40B 50/06 (2013.01); C12M 45/09 (2013.01); C12P 19/34 (2013.01); B01L 3/502753 (2013.01); B01L 3/502761 (2013.01); B01L 2400/086 (2013.01); B01L 2200/0652 (2013.01); B01L 2300/0819 (2013.01);
Abstract
Systems and methods for processing fluid samples are disclosed. Fluid sample processing is accomplished using a series of microfluidic bump arrays include an automated and integrated system for sorting particles from a biological sample, lysing those particles to expose total RNA or DNA, purifying the RNA or DNA, processing the RNA or DNA by chemical or enzymatic modification, to select RNA or DNA molecules by size, or to generate, optionally, a sequencing library. The sequencing library is suitable for use in next generation sequencing ('NGS').